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Retropinacol/Cross-pinacol Coupling Reactions – A Catalytic Access to 1,2-Unsymmetrical Diols
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JoVE Journal Chemistry
Retropinacol/Cross-pinacol Coupling Reactions – A Catalytic Access to 1,2-Unsymmetrical Diols

Retropinacol/Cross-pinacol Coupling Reactions – A Catalytic Access to 1,2-Unsymmetrical Diols

English

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12,796 Views

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10:12 min

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April 04, 2014

DOI:

10.3791/51258-v

DOI:
10.3791/51258-v

•

10:12 min
April 04, 2014

•

5 Views
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1Department of Chemistry,Humboldt University of Berlin

Summary

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A novel account for the synthesis of unsymmetrical 1,2-diols based on a retropinacol/cross-pinacol coupling mechanism is described. Due to the catalytic execution of this reaction a considerable improvement compared to conventional cross-pinacol couplings is achieved.

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Cite this Article

Scheffler, U., Mahrwald, R. Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols. J. Vis. Exp. (86), e51258, doi:10.3791/51258 (2014).

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