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November 06, 2012
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The intraluminal middle cerebral occlusion model in mice is herein presented. The extent of cerebral infarct is evaluated by a neurologic score and cresyl violet staining, an alternative staining to TTC, offering the great advantage to test in parallel many interest markers.
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Mouse ModelIntraluminal MCAOCerebral Infarct EvaluationCresyl Violet StainingStrokeIschemic StrokeAcute Ischemic StrokeIschemic Stroke ModelsRodent ModelsGlobal Cerebral IschemiaFocal Cerebral IschemiaMiddle Cerebral Artery OcclusionKoizumi Et Al.Genetic Manipulation In MiceTransient MCA Occlusion ProcedureInfarct VolumeCommercial Silicon Coated MonofilamentsSubarachnoid HemorrhagesZeiss Stereo-microscope Stemi 2000
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Rousselet, E., Kriz, J., Seidah, N. G. Mouse Model of Intraluminal MCAO: Cerebral Infarct Evaluation by Cresyl Violet Staining. J. Vis. Exp. (69), e4038, doi:10.3791/4038 (2012).
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