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November 11, 2011
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As manual dexterity is a prerogative mainly of primates, behavioral tasks have been developed in macaque monkeys. Four reach and grasp prehension tasks, measuring hand manipulation ability and force, allow to establish functional recovery after a lesion of the central nervous system and to test the effect of a treatment.
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Behavioral AssessmentManual DexterityNon-human PrimatesCorticospinal TractMotor AbilitySmall Objects ManipulationLesionMotor Cortical AreasCervical Cord LesionHand ParalysisTetraplegicHemiplegic PatientsFunctional RecoveryTherapeutic StrategiesCell TherapyInhibitory Axonal Growth MoleculesGrowth FactorsFeasibilityEfficacySecurityTreatmentCentral Nervous SystemRodentsMacaque Monkeys
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Schmidlin, E., Kaeser, M., Gindrat, A. D., Savidan, J., Chatagny, P., Badoud, S., Hamadjida, A., Beaud, M., Wannier, T., Belhaj-Saif, A., Rouiller, E. M. Behavioral Assessment of Manual Dexterity in Non-Human Primates. J. Vis. Exp. (57), e3258, doi:10.3791/3258 (2011).
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