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Axon Stretch Growth: The Mechanotransduction of Neuronal Growth
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Axon Stretch Growth: The Mechanotransduction of Neuronal Growth

Axon Stretch Growth: The Mechanotransduction of Neuronal Growth

English

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16,566 Views

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11:46 min

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August 10, 2011

DOI:

10.3791/2753-v

DOI:
10.3791/2753-v

•

11:46 min
August 10, 2011

•

8 Views
, ,
1Departments of Biomedical Engineering,New Jersey Institute of Technology, 2Graduate School of Biomedical Sciences,University of Medicine and Dentistry of New Jersey

Summary

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A unique tissue engineering method was developed to elongate numerous nerve fibers in culture by recapitulating axon stretch growth; a form of nervous system growth whereby nerves elongate in conjunction with growth of the enlarging body.

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Loverde, J. R., Tolentino, R. E., Pfister, B. J. Axon Stretch Growth: The Mechanotransduction of Neuronal Growth. J. Vis. Exp. (54), e2753, doi:10.3791/2753 (2011).

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