JOVE JOURNAL

Cancer Research

Showing 145 - 156 in 594 videos.

Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model

Claudia Manriquez Roman^2,3,4,5, R. Leo Sakemura², Brooke L. Kimball², Fang Jin, Roman H. Khadka, Mohamad M. Adada², Elizabeth L. Siegler², Aaron J. Johnson, Saad S. Kenderian^2,6

¹T Cell Engineering Laboratory,Mayo Clinic, Rochester, ²Division of Hematology,Mayo Clinic, Rochester, ³Mayo Clinic Graduate School of Biomedical Sciences,Mayo Clinic, Rochester, ⁴Department of Molecular Medicine,Mayo Clinic, Rochester, ⁵Regenerative Sciences PhD Program,Mayo Clinic, Rochester, ⁶Department of Immunology,Mayo Clinic, Rochester

Journal (Cancer Research)

Development of a ⁶⁸Gallium-Labeled D-Peptide PET Tracer for Imaging Programmed Death-Ligand 1 Expression

Lulu Zhang*¹, Siqi Zhang*², Wenyu Wu, Xingkai Wang, Jieting Shen, Dongyuan Wang, Kuan Hu*^2,3, Ming-Rong Zhang*³, Feng Wang*¹, Rui Wang*²

¹Department of Nuclear Medicine, Nanjing First Hospital,Nanjing Medical University, ²State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College, ³Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science,National Institutes for Quantum Science and Technology, ⁴Department of Pharmacy, Union Hospital, Tongji Medical College,Huazhong University of Science and Technology

Journal (Cancer Research)

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Huayun Yan, Yingfang Ma, Xinyue Zhou, Yushuang He, Yang Liu, Carlos Caulin, Leiming Wang, Heng Xu⁶, Han Luo⁶

¹State Key Laboratory of Biotherapy and Cancer Center, West China Hospital,Sichuan University and Collaborative Innovation Center, ²Division of Thyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, Department of General Surgery, West China Hospital,Sichuan University, ³Department of Ultrasound, West China Hospital of Sichuan University,Sichuan University, ⁴Department of Otolaryngology-Head & Neck Surgery and University of Arizona Cancer Center,University of Arizona, ⁵Center for Translational Medicine,Shenzhen Bay Laboratory, ⁶Division of Laboratory Medicine/Research Centre of Clinical Laboratory Medicine, West China Hospital,Sichuan University

Journal (Cancer Research)

An Enrichment Method for Small Extracellular Vesicles Derived from Liver Cancer Tissue

Xiaoxing Wang², Jie Chen², Zhengzhe Li², Defa Huang², Xiaomei Yi², Jiyang Wu², Tianyu Zhong²

¹The First School of Clinical Medicine,Gannan Medical University, ²Laboratory Medicine,First Affiliated Hospital of Gannan Medical University

Journal (Cancer Research)

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Jin-Han Bae, Jay Jeong, Byung Chul Kim, Sung-Hun Lee

¹Clinomics Inc.

Journal (Cancer Research)

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Claire Wunker², Karolina Piorkowska, Ben Keunen, Yael Babichev, Suzanne M. Wong⁴, Maximilian Regenold, Michael Dunne, Julia Nomikos², Maryam Siddiqui, Samuel Pichardo, Warren Foltz, Adam C. Waspe⁸, Justin T. Gerstle⁹, James M. Drake^3,4,10, Rebecca A. Gladdy^2,10

¹Institute of Medical Science,University of Toronto, ²Lunenfeld-Tanenbaum Research Institute,Mount Sinai Hospital, ³The Wilfred and Joyce Posluns Centre for Image-Guided Innovation and Therapeutic Intervention,The Hospital for Sick Children, ⁴Institute of Biomedical Engineering,University of Toronto, ⁵Leslie Dan Faculty of Pharmacy,University of Toronto, ⁶Departments of Radiology and Clinical Neurosciences,University of Calgary, ⁷Department of Radiation Oncology,University of Toronto, ⁸Department of Medical Imaging,University of Toronto, ⁹Department of Pediatric Surgery,University of Toronto, ¹⁰Department of Surgery,University of Toronto

Journal (Cancer Research)

Generation and Culturing of High-Grade Serous Ovarian Cancer Patient-Derived Organoids

Olivia Graham*¹, Jeimmy Rodriguez*¹, Lillian van Biljon, Bisiayo Fashemi, Emily Graham, Katherine Fuh², Dineo Khabele, Mary Mullen

¹Washington University in St. Louis, ²University of California San Francisco

Journal (Cancer Research)

Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice

Fenghua Qian, Brooke E. Arner, Shaneice K. Nettleford, Robert F. Paulson, K. Sandeep Prabhu

¹Department of Veterinary and Biomedical Sciences, Center for Molecular Immunology and Infectious Disease and Center for Molecular Toxicology and Carcinogenesis, Penn State Cancer Institute,The Pennsylvania State University

Journal (Cancer Research)

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Samuel Flashner*¹, Cecilia Martin*^1,2, Norihiro Matsuura, Masataka Shimonosono, Yasuto Tomita, Masaki Morimoto, Ogoegbunam Okolo, Victoria X. Yu³, Anuraag S. Parikh³, Andres J. P. Klein-Szanto, Kelley Yan², Joel T. Gabre⁵, Chao Lu⁶, Fatemeh Momen-Heravi⁷, Anil K. Rustgi⁵, Hiroshi Nakagawa^2,5

¹Herbert Irving Comprehensive Cancer Center,Columbia University, ²Organoid and Cell Culture Core, Columbia University Digestive and Liver Diseases Research Center,Columbia University, ³Department of Otolaryngology, Head and Neck Surgery,Columbia University, ⁴Histopathology Facility,Fox Chase Cancer Center, ⁵Division of Digestive and Liver Diseases, Department of Medicine,Columbia University, ⁶Department of Genetics and Development,Columbia University, ⁷Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine,Columbia University

Journal (Cancer Research)

Multiparametric Tumor Organoid Drug Screening Using Widefield Live-Cell Imaging for Bulk and Single-Organoid Analysis

Maxim Le Compte, Edgar Cardenas De La Hoz, Sofía Peeters, Evelien Smits, Filip Lardon, Geert Roeyen³, Steve Vanlanduit, Hans Prenen⁴, Marc Peeters⁴, Abraham Lin⁵, Christophe Deben

¹Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON),University of Antwerp, ²Industrial Vision Lab,University of Antwerp, ³Department of Hepatobiliary Transplantation and Endocrine Surgery,University Hospital Antwerp (UZA), ⁴Department of Oncology,University Hospital Antwerp (UZA), ⁵Plasma Lab for Applications in Sustainability and Medicine ANTwerp (PLASMANT),University of Antwerp

Journal (Cancer Research)

Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors

Jordi M. Lanis*¹, Matthew S. Lewis*¹, Hannah Strassburger, Kristina Larsen, Stacey M. Bagby, Adrian T. A. Dominguez, Juan A. Marín-Jiménez, Roberta Pelanda, Todd M. Pitts, Julie Lang

¹Department of Immunology and Microbiology, School of Medicine,University of Colorado Denver Anschutz Medical Campus, ²Division of Oncology, School of Medicine,University of Colorado Denver Anschutz Medical Campus, ³Department of Medical Oncology,Catalan Institute of Oncology (ICO-L'Hospitalet)

Journal (Cancer Research)

Establishing 3-Dimensional Spheroids from Patient-Derived Tumor Samples and Evaluating their Sensitivity to Drugs

Neta Moskovits², Ella Itzhaki², Nataly Tarasenko², Eva Chausky², Avital Bareket-Samish, Aleksandr Kaufman², Raisa Meerson², Salomon M. Stemmer^2,4

¹Felsenstein Medical Research Center, ²Davidoff Center, Rabin Medical Center, ³BioInsight Ltd., ⁴Sackler Faculty of Medicine,Tel Aviv University

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