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Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
JoVE Journal
神経科学
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JoVE Journal 神経科学
Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

6,509 Views

05:40 min

July 29, 2021

DOI:

05:40 min
July 29, 2021

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概要

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The most notable symptom of migraine is severe head pain, and it is hypothesized that this is mediated by sensory neurons innervating the meninges. Here, we present a method to locally apply substances to the dura in a minimally invasive manner while using facial hypersensitivity as an output.

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