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June 13, 2020
DOI:
10.3791/61113-v
用微泡剂聚焦超声波可以聚焦和瞬时打开血脑屏障。这项技术已被用于通过血脑屏障提供广泛的制剂。本文提供了一个详细的协议,本地化交付给啮齿动物的大脑有或没有MRI指导。
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Rich, M., Whitsitt, Q., Lubin, F., Bolding, M. A Benchtop Approach to the Location Specific Blood Brain Barrier Opening using Focused Ultrasound in a Rat Model. J. Vis. Exp. (160), e61113, doi:10.3791/61113 (2020).
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