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A Galleria mellonella Oral Administration Model to Study Commensal-Induced Innate Immune Responses
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JoVE Journal 免疫学と感染
A Galleria mellonella Oral Administration Model to Study Commensal-Induced Innate Immune Responses

A Galleria mellonella Oral Administration Model to Study Commensal-Induced Innate Immune Responses

7,732 Views

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06:32 min

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March 21, 2019

DOI:

10.3791/59270-v

DOI:
10.3791/59270-v

•

06:32 min
March 21, 2019

•

12 Views
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1Department for Medical Microbiology, Hygiene, Interfacultary Institute for Microbiology, Infection Medicine,University of Tübingen

概要

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Here, we provide a detailed protocol for an oral administration model using Galleria mellonella larvae and how to characterize induced innate immune responses. Using this protocol, researchers without practical experience will be able to use the G. mellonella force-feeding method.

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Lange, A., Schäfer, A., Frick, J. A Galleria mellonella Oral Administration Model to Study Commensal-Induced Innate Immune Responses. J. Vis. Exp. (145), e59270, doi:10.3791/59270 (2019).

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