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Subpiaal Adeno-geassocieerde Virus 9 (AAV9) Vector Levering in Volwassene Muizen
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JoVE Journal 神経科学
Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice
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Subpiaal Adeno-geassocieerde Virus 9 (AAV9) Vector Levering in Volwassene Muizen

16,934 Views

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08:32 min

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July 13, 2017

DOI:

10.3791/55770-v

DOI:
10.3791/55770-v

•

08:32 min
July 13, 2017

•

19 Views
, , , , , , , , , , , , ,
1Neuroregeneration Laboratory, Department of Anesthesiology,University of California, San Diego, 2Institute of Animal Physiology and Genetics,Czech Academy of Sciences, 3Department of Neurosurgery,University of California, San Diego, 4Institute of Neurobiology,Slovak Academy of Sciences

概要

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Het doel van de huidige studie was het ontwikkelen en valideren van de kracht en de veiligheid van de lever-adeno-geassocieerde virus 9 (AAV9) -gemedieerde genafgifte door gebruik te maken van een nieuwe subpiale genafgifte techniek bij volwassen muizen.

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Tadokoro, T., Miyanohara, A., Navarro, M., Kamizato, K., Juhas, S., Juhasova, J., Marsala, S., Platoshyn, O., Curtis, E., Gabel, B., Ciacci, J., Lukacova, N., Bimbova, K., Marsala, M. Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice. J. Vis. Exp. (125), e55770, doi:10.3791/55770 (2017).

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