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BMP 길항제 Grem2를 사용하여 다 능성 줄기 세포에서 심방 심근의 차별화
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発生生物学
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JoVE Journal 発生生物学
Differentiation of Atrial Cardiomyocytes from Pluripotent Stem Cells Using the BMP Antagonist Grem2

BMP 길항제 Grem2를 사용하여 다 능성 줄기 세포에서 심방 심근의 차별화

DOI:

08:52 min

March 10, 2016

,

  • 00:05標題
  • 00:33Murine Embryonic Stem Cell (mESC) Culture and Passaging
  • 03:16Embryoid Body (EB) Preparation and Grem2 Treatment
  • 06:12Results: Grem2-induction of Cardiomyocyte Differentiation
  • 08:00Conclusion

概要

自動翻訳

Generating cardiomyocytes from pluripotent stem cells in vitro allows access to large amounts of cardiac tissue in vitro for basic science and clinical applications. This protocol uses the atrializing factor Grem2 to both increase the numbers of cardiomyocytes obtained and to generate cardiomyocytes with an atrial phenotype.

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