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Esecuzione permanente distale Medio cerebrale con arteria carotide comune di occlusione in ratti anziani per studiare corticale Ischemia con disabilità sostenuta
JoVE Journal
医学
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JoVE Journal 医学
Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
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Esecuzione permanente distale Medio cerebrale con arteria carotide comune di occlusione in ratti anziani per studiare corticale Ischemia con disabilità sostenuta

20,740 Views

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09:11 min

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February 23, 2016

DOI:

10.3791/53106-v

DOI:
10.3791/53106-v

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09:11 min
February 23, 2016

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22 Views
, , , , , , , ,
1Wolfson Centre for Age-Related Diseases,King’s College London, University of London, 2Department of Neuroimaging, James Black Centre, Institute of Psychiatry,King’s College London, University of London, 3Institute of Neuroscience and Psychology, Wellcome Surgical Institute, College of Medical, Veterinary and Life Sciences,University of Glasgow, Glasgow, 4Research Service,Edward Hines Jr. VA Hospital, 5Neurology Service,Edward Hines Jr. VA Hospital, 6Department of Molecular Pharmacology and Therapeutics, Neuroscience Research Institute,Loyola University Chicago, 7Department of Oncology, The Gray Institute for Radiation, Oncology and Biology,University of Oxford

概要

Automatically generated

Qui vi presentiamo un protocollo per la produzione di distale occlusione dell'arteria cerebrale media permanente anziani ratti femmina con occlusione simultanea delle arterie carotidi a generare grandi infarti corticali e deficit sostenuti. Mostriamo conferma della dimensione della lesione utilizzando la risonanza magnetica strutturale a 24 ore e 8 settimane dopo l'ictus.

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Cite this Article

Wayman, C., Duricki, D. A., Roy, L. A., Haenzi, B., Tsai, S., Kartje, G., Beech, J. S., Cash, D., Moon, L. Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability. J. Vis. Exp. (108), e53106, doi:10.3791/53106 (2016).

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