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Kwantitatieve Analyse van Klimmen Defecten in een Drosophila model van neurodegeneratieve aandoeningen
JoVE Journal
神経科学
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JoVE Journal 神経科学
Quantitative Analysis of Climbing Defects in a Drosophila Model of Neurodegenerative Disorders

Kwantitatieve Analyse van Klimmen Defecten in een Drosophila model van neurodegeneratieve aandoeningen

DOI:

06:30 min

June 13, 2015

, , , , , , , ,

  • 00:05標題
  • 01:27Fly Collection and Climbing Assay
  • 03:57Analysis of Fly Performance
  • 04:54Results: Climbing Deficits in a Drosophila Model of Neurodegenerative Disorders
  • 06:01Conclusion

概要

自動翻訳

We present an optimized inexpensive and reliable negative geotaxis assay in Drosophila melanogaster as a model for neurodegenerative disorders. Being more sensitive to mild locomotor defects, this assay will help screen for potential genetic interactions and drug targets.

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