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ノルアドレナリンβ遮断薬によるヒトにおける恐怖記憶の再固定を乱す
章
- 00:05標題
- 00:59Fear Potentiated Startle and Shock Electrodes
- 03:03Fear Acquisition – Day 1
- 04:27Memory Reactivation – Day 2
- 05:59Test – Day 3
- 07:20Results: Disrupted Fear Memory after Propranolol Treatment
- 08:08Conclusion
Disrupting reconsolidation is a promising approach to dampen the behavioral expression of fear memory in patients with anxiety disorders or posttraumatic stress disorder. In a series of human fear conditioning studies we showed that disrupting reconsolidation by the noradrenergic β-blocker propranolol is very effective in erasing conditioned fear responding.
