Tuberculosis and malaria are two of the most prevalent infections in humans and major causes of morbidity and mortality in impoverished populations in the tropics. We established an experimental model system to study outcome of malaria-tuberculosis coinfection in mice after challenge with both pathogens via their natural route of infection.
Mueller, A., Behrends, J., Blank, J., Schaible, U. E., Schneider, B. E. An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei. J. Vis. Exp. (84), e50829, doi:10.3791/50829 (2014).