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Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
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June 13, 2014
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An example of a nano drug based on polymalic acid is presented towards the rational design of personalized medicine that is applicable to cancer. It describes the synthesis of a nano drug to treat Her2-positive human breast cancer in a nude mouse.
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Ljubimova, J. Y., Ding, H., Portilla-Arias, J., Patil, R., Gangalum, P. R., Chesnokova, A., Inoue, S., Rekechenetskiy, A., Nassoura, T., Black, K. L., Holler, E. Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?. J. Vis. Exp. (88), e50668, doi:10.3791/50668 (2014).
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