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Granulócitos-dependente Blistering pele induzida por auto-anticorpos
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JoVE Journal 免疫学と感染
Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulócitos-dependente Blistering pele induzida por auto-anticorpos

10,386 Views

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12:23 min

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October 12, 2012

DOI:

10.3791/4250-v

DOI:
10.3791/4250-v

•

12:23 min
October 12, 2012

•

4 Views
, ,
1皮膚学部,University of Freiburg , 2Kepler High School Freiburg, 3Centre for Biological Signalling Studies (BIOSS),University of Freiburg

概要

Automatically generated

No modelo animal descrito no nosso trabalho, purificou anticorpos IgG contra uma extensão de 200 aminoácidos (aa 757-967) de colagénio VII são injectados repetidamente em ratinhos que reproduzem o fenótipo empolar, bem como a histo-e imunopatológicas características de humano epidermólise bolhosa adquirida (EBA)<sup> 1</sup>.

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Cite this Article

Csorba, K., Sitaru, S., Sitaru, C. Granulocyte-dependent Autoantibody-induced Skin Blistering. J. Vis. Exp. (68), e4250, doi:10.3791/4250 (2012).

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