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Polymer Microarrays for High Throughput Discovery of Biomaterials
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January 25, 2012
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A description of the formation of a polymer microarray using an on-chip photopolymerization technique. The high throughput surface characterization using atomic force microscopy, water contact angle measurements, X-ray photoelectron spectroscopy and time of flight secondary ion mass spectrometry and a cell attachment assay is also described.
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Polymer MicroarraysHigh Throughput DiscoveryBiomaterialsCombinatorial LibraryOn-chip PhotopolymerizationMonomer SolutionsRobotic Printing DeviceUV IrradiationBiological AssaysStem Cell AttachmentCell SortingBacterial AdhesionHigh Throughput Surface CharacterizationWater Contact AngleAtomic Force MicroscopyX-ray Photoelectron SpectroscopyTime-of-flight Secondary Ion Mass SpectrometryMolecular Moiety
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Hook, A. L., Chang, C., Yang, J., Scurr, D. J., Langer, R., Anderson, D. G., Atkinson, S., Williams, P., Davies, M. C., Alexander, M. R. Polymer Microarrays for High Throughput Discovery of Biomaterials. J. Vis. Exp. (59), e3636, doi:10.3791/3636 (2012).
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