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免疫学と感染
Assessing Serum Neutralization Against SARS-CoV-2 with Pseudotyped Viruses

Assessing Serum Neutralization Against SARS-CoV-2 with Pseudotyped Viruses

November 21, 2023

Author Spotlight: Studying Host-Virus Interactions with Pseudotyped Viruses

01:03 min
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SARS-CoV-2 Pseudotype Virus Production and Serum Neutralization Assay

04:50 min
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1Department of Neuroscience, Biomedicine and Movement,University of Verona, 2Laboratory of Molecular Neurovirology, Faculty of Health Science,University of Brasília, 3Viral Pseudotype Unit, Medway School of Pharmacy,Universities of Kent and Greenwich at Medway

概要

Pseudotyped viruses (PVs) are replication-defective virions that are used to study host-virus interactions under safer conditions than handling authentic viruses. Presented here is a detailed protocol that shows how SARS-CoV-2 PVs can be used to test the neutralizing ability of patients’ serum after COVID-19 vaccination.

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