Rivista
/
Neuroscienze
/
帕金森病的6-羟基多巴胺大鼠模型
JoVE Journal
Neuroscienze
Author Produced
È necessario avere un abbonamento a JoVE per visualizzare questo.  Accedi o inizia la tua prova gratuita.
JoVE Journal Neuroscienze
The 6-hydroxydopamine Rat Model of Parkinson’s Disease
Please note that all translations are automatically generated. Click here for the English version.

帕金森病的6-羟基多巴胺大鼠模型

DOI:
10.3791/62923-v

•

08:10 min

•

October 27, 2021

•

, , , , ,
1Department of Psychology, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto,University of São Paulo

Capitoli

  • 00:04Introduction
  • 01:00Training for Stepping and Test
  • 03:18Surgical Procedure
  • 06:06Results: Results of Stepping Test and Histological Analysis
  • 07:30Conclusion

Summary

Traduzione automatica

Traduzione automatica

6-羟基多巴胺（6-OHDA）模型已经使用了几十年，以推进对帕金森病的理解。在该协议中，我们展示了如何通过在内侧前脑束中注射6-OHDA来执行大鼠的单侧黑质纹状体病变，评估运动缺陷并使用步进测试预测病变。

Tags

Keywords: 6-hydroxydopamineParkinson’s DiseaseRat ModelNigrostriatal LesionsMedial Forebrain BundleStepping TestMotor DeficitsDopaminergic NeuronsSubstantia NigraNeurodegeneration

Article

Embed

AGGIUNGI ALLA PLAYLIST

Usage Statistics

Video correlati

check_url/it/62923?article_type=v

在阿尔茨海默氏症小鼠模型神经炎斑检测
check_url/it/62923?article_type=v

方法来描述自发和惊吓引起的步态中的鱼藤酮诱导的帕金森病模型<em>果蝇</em
check_url/it/62923?article_type=v

在实验视神经脱髓鞘模型大鼠视觉诱发电位记录
check_url/it/62923?article_type=v

从单体和体内使用的Α-syr核 in 预成型纤维的产生
check_url/it/62923?article_type=v

描述眼动参数与无视力帕金森病患者眼动功能的关系
check_url/it/62923?article_type=v

将RatWalker系统应用于帕金森病遗传大鼠模型中的步态分析
check_url/it/62923?article_type=v

使用自动图像分析对啮齿动物模型的亚斯坦蒂娅尼格拉多巴明神经元密度进行半定量测定
check_url/it/62923?article_type=v

通过螺纹栓塞方法建立高级射手座-鼻塞的鼠模型
check_url/it/62923?article_type=v

左旋多巴诱导的帕金森病大鼠模型中运动障碍的诱导与评估
check_url/it/62923?article_type=v

分析编码人类α突触核蛋白的腺相关病毒载体诱导的帕金森病小鼠模型

Read Article