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Neuroscience

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JoVE Journal Neuroscience
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
 

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Article DOI: 10.3791/62567-v • 09:14 min • June 18th, 2021
June 18th, 2021 •
1,2, 2, 2,4, 1,3,5, 2
1Department of Neurosurgery, Rigshospitalet, 2Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, 3Department of Clinical Medicine, University of Copenhagen, 4Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, 5Department of Clinical Neuroscience, Karolinska Institutet

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Subarachnoid hemorrhage continues to carry a high burden of mortality and morbidity in man. To facilitate further research into the condition and its pathophysiology, a pre-chiasmatic, single injection model is presented.

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Pre-Chiasmatic Single Injection Autologous Blood Experimental Subarachnoid Hemorrhage Rat Model Pathophysiological Mechanisms Consequences Therapies Burden Of Disease Reproducible Technique Human Subarachnoid Hemorrhage ICP Probe Polythene Tubing Silicone Tubing Sprague Dawley Rat Stereotaxic Frame Local Anesthesia Skin Incision Atlantooccipital Membrane Neck Musculature ICP Transducer
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