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由加德纳菌阴道膀胱暴露在小鼠中引发的复发性大肠杆菌尿路感染
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December 04, 2020
DOI:
1Department of Molecular Microbiology,Washington University School of Medicine in Saint Louis, 2Center for Women’s Infectious Disease Research,Washington University School of Medicine in Saint Louis, 3Center for Cellular Imaging,Washington University School of Medicine in Saint Louis, 4Department of Obstetrics and Gynecology,Washington University School of Medicine in Saint Louis, 5Department of Pediatrics,Washington University School of Medicine in Saint Louis, 6Fred Hutchinson Cancer Research Center, 7TESCAN USA, Inc., 8University of California San Diego
Summary
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展示了产尿道 大肠杆菌 （UPEC） 经尿道接种以建立潜伏细胞内膀胱储液囊的小鼠模型，随后膀胱暴露于 阴道 G. 以诱导复发性 UPEC UTI。还证明了细菌的计数，尿液细胞学检查以及原位膀胱固定和扫描电子显微镜处理。
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Cite this Article
O'Brien, V. P., Joens, M. S., Lewis, A. L., Gilbert, N. M. Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice. J. Vis. Exp. (166), e61967, doi:10.3791/61967 (2020).
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