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Primer Embriyonik Fare Orta Beyin Dopamin Nöronlarında Pre-formed Fibril Indüklenen α-Sinüklein Birikiminin İncelendirilmesi

JoVE Journal
Neuroscienze

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JoVE Journal Neuroscienze

Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons

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Primer Embriyonik Fare Orta Beyin Dopamin Nöronlarında Pre-formed Fibril Indüklenen α-Sinüklein Birikiminin İncelendirilmesi

9,911 Views

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10:03 min

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August 16, 2020

DOI:

10.3791/61118-v

DOI:

10.3791/61118-v

•

10:03 min

August 16, 2020

•

2 Views

Safak Er, Irena Hlushchuk, Mikko Airavaara, Piotr Chmielarz³, Andrii Domanskyi

¹Institute of Biotechnology, HiLIFE,University of Helsinki, ²Neuroscience Center, HiLIFE,University of Helsinki, ³Department of Brain Biochemistry, Maj Institute of Pharmacology,Polish Academy of Sciences

Tags

Alpha-synuclein Preformed Fibrils Primary Dopamine Neurons Parkinson’s Disease Neurodegenerative Disease Protein Accumulation Cell Culture High-throughput Screening Image Analysis Neuron Function Molecular Mechanisms

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