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High-Frequency Ultrasound Echocardiography to Assess Zebrafish Cardiac Function
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High-Frequency Ultrasound Echocardiography to Assess Zebrafish Cardiac Function
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March 12, 2020
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We describe a protocol to assess heart morphology and function in adult zebrafish using high-frequency echocardiography. The method allows visualization of the heart and subsequent quantification of functional parameters, such as heart rate (HR), cardiac output (CO), fractional area change (FAC), ejection fraction (EF), and blood inflow and outflow velocities.
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Evangelisti, A., Schimmel, K., Joshi, S., Shah, K., Fisch, S., Alexander, K. M., Liao, R., Morgado, I. High-Frequency Ultrasound Echocardiography to Assess Zebrafish Cardiac Function. J. Vis. Exp. (157), e60976, doi:10.3791/60976 (2020).
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