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Transplantation de progéniteurs interneuron corticales génétiquement modifiés dans les cerveaux de souris postnatales précoces
JoVE Journal
Neuroscienze
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JoVE Journal Neuroscienze
Transplantation of Chemogenetically Engineered Cortical Interneuron Progenitors into Early Postnatal Mouse Brains
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Transplantation de progéniteurs interneuron corticales génétiquement modifiés dans les cerveaux de souris postnatales précoces

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00:06 min

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August 26, 2019

DOI:

10.3791/59568-v

DOI:
10.3791/59568-v

•

00:06 min
August 26, 2019

•

1 Views
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1Nervous System Development and Homeostasis Laboratory,The Francis Crick Institute, 2Neuroscience Centre,Biomedical Sciences Research Centre “Al. Fleming”, 3Centre for Developmental Neurobiology,King’s College London

Summary

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Ici nous présentons un protocole, conçu pour employer des outils chimiogénétiques pour manipuler l'activité des progéniteurs interneurons corticaux transplantés dans le cortex des souris postnatales tôt.

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Denaxa, M., Neves, G., Burrone, J., Pachnis, V. Transplantation of Chemogenetically Engineered Cortical Interneuron Progenitors into Early Postnatal Mouse Brains. J. Vis. Exp. (150), e59568, doi:10.3791/59568 (2019).

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