/

/

וקטור lentiviral פלטפורמה למסירה יעיל של כלי עריכת Epigenome לתוך האדם המושרה מודלים המחלה נגזר תאי גזע Pluripotent

JoVE Journal
Genetica

È necessario avere un abbonamento a JoVE per visualizzare questo. Accedi o inizia la tua prova gratuita.

JoVE Journal Genetica

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models

Please note that all translations are automatically generated. Click here for the English version.

וקטור lentiviral פלטפורמה למסירה יעיל של כלי עריכת Epigenome לתוך האדם המושרה מודלים המחלה נגזר תאי גזע Pluripotent

9,226 Views

•

13:47 min

•

March 29, 2019

DOI:

10.3791/59241-v

DOI:

10.3791/59241-v

•

13:47 min

March 29, 2019

•

1 Views

Lidia Tagliafierro², Ekaterina Ilich, Malik Moncalvo, Jeffrey Gu, Ahila Sriskanda², Carole Grenier, Susan K. Murphy, Ornit Chiba-Falek², Boris Kantor

¹Department of Neurology,Duke University Medical Center, ²Center for Genomic and Computational Biology,Duke University Medical Center, ³Viral Vector Core,Duke University Medical Center, ⁴Division of Gynecologic Oncology, Department of Obstetrics and Gynecology,Duke University Medical Center

Tags

Lentiviral Vector Epigenome Editing Human Induced Pluripotent Stem Cells Disease Models CRISPR/Cas Alpha-synuclein Gene Expression Guide RNA Molecular Cloning Plasmid Construction Neural Progenitor Cells DNA Methyltransferase (DNMT3A)

Read Article