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A Microphysiologic Platform for Human Fat: Sandwiched White Adipose Tissue
JoVE Journal
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A Microphysiologic Platform for Human Fat: Sandwiched White Adipose Tissue

A Microphysiologic Platform for Human Fat: Sandwiched White Adipose Tissue

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08:14 min

August 15, 2018

DOI:

08:14 min
August 15, 2018

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Summary

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White adipose tissue (WAT) has critical deficiencies in its current primary culture models, hindering pharmacological development and metabolic studies. Here, we present a protocol to produce an adipose microphysiological system by sandwiching WAT between sheets of stromal cells. This construct provides a stable and adaptable platform for primary WAT culture.

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