/
/
פיתוח מודל כבד אתנול-induced fibrotic דג הזברה ללמוד ובתאים בתיווך תא התחדשות Hepatocyte
È necessario avere un abbonamento a JoVE per visualizzare questo. Accedi o inizia la tua prova gratuita.
פיתוח מודל כבד אתנול-induced fibrotic דג הזברה ללמוד ובתאים בתיווך תא התחדשות Hepatocyte
9,019 Views
•
10:42 min
•
May 13, 2016
DOI:
Summary
Automatically generated
Sustained fibrosis with deposition of excessive extracellular matrix proteins leads to cirrhosis. Alcohol abuse is one of the main causes of severe liver disease. We established an ethanol-induced zebrafish fibrotic liver model to study the mechanisms and strategies of promoting hepatocyte regeneration upon alcohol-induced injury.
Read Article
Cite this Article
Huang, M., Xu, J., Shin, C. H. Development of an Ethanol-induced Fibrotic Liver Model in Zebrafish to Study Progenitor Cell-mediated Hepatocyte Regeneration. J. Vis. Exp. (111), e54002, doi:10.3791/54002 (2016).
Copy