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פרוטוקול מתח מתון כרוני בלתי צפוי לתסמיני דיכאון ייזום, שינויים התנהגותיים ותוצאות בריאותיות שליליות במכרסמים
JoVE Journal
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JoVE Journal Comportamento
An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
DOI:

06:55 min

December 02, 2015

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Capitoli

  • 00:05Titolo
  • 01:37Unpredictable Chronic Mild Stress Protocol
  • 03:50Animal Monitoring and Grooming Scores
  • 04:37Behavioral Testing: The Sucrose Splash and Tail Suspension Tests
  • 05:15Results: Measures of Physiological Changes in Mice Due to Unpredictable Chronic Mild Stress
  • 06:12Conclusion

Summary

Traduzione automatica

The unpredictable chronic mild stress (UCMS) protocol is a validated method for studying behavioral and physiological changes associated with chronic stress and depressive symptoms. Eight weeks of imposition of the UCMS protocol induces behavioral changes and poor health outcomes in rodents of either gender.

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