JoVE Journal
Neuroscience
Neuroscience
This Contenuto is Open Access.
Capitoli
Riepilogo
We demonstrate the fabrication, calibration and properties of two types of ion-selective microelectrodes (double-barreled and concentric) for measurement of ion concentrations in brain tissue. These are then used in the mouse hippocampal slice preparation to show that excitatory activity changes both extracellular potassium and sodium concentrations.