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زرع Miniosmotic مضخات والتسليم استشفاف المسالك لدراسة إعادة تنظيم الدماغ في حالة المرضية
JoVE Journal
Neuroscienze
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JoVE Journal Neuroscienze
Implantation of Miniosmotic Pumps and Delivery of Tract Tracers to Study Brain Reorganization in Pathophysiological Conditions
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زرع Miniosmotic مضخات والتسليم استشفاف المسالك لدراسة إعادة تنظيم الدماغ في حالة المرضية

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10:32 min

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January 18, 2016

DOI:

10.3791/52932-v

DOI:
10.3791/52932-v

•

10:32 min
January 18, 2016

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1 Views
, , , ,
1Department of Neurology,University of Duisburg-Essen, 2Neuroscience Unit,Institute for Advanced Studies (IDEA), 3Department of Cell Biology,Simon Bolivar University

Summary

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In order to study brain reorganization under pathological conditions we used miniosmotic pumps for direct protein delivery into the brain circumventing the blood brain barrier. Tract tracers are then injected to study alterations in brain connectivity under the influence of the protein.

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Cite this Article

Sanchez-Mendoza, E. H., Carballo, J., Longart, M., Hermann, D. M., Doeppner, T. R. Implantation of Miniosmotic Pumps and Delivery of Tract Tracers to Study Brain Reorganization in Pathophysiological Conditions. J. Vis. Exp. (107), e52932, doi:10.3791/52932 (2016).

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