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Forward Genetica Schermen Met behulp van macrofagen te identificeren<em> Toxoplasma gondii</em> Genen Belangrijk voor Weerstand tegen IFN-γ-Dependent Cell Autonome Immuniteit
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Forward Genetica Schermen Met behulp van macrofagen te identificeren<em> Toxoplasma gondii</em> Genen Belangrijk voor Weerstand tegen IFN-γ-Dependent Cell Autonome Immuniteit
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March 12, 2015
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Forward genetics is a powerful approach to identify genes in intracellular pathogens important for resistance to cell autonomous immunity. The current approach uses innate immune cells, specifically macrophages, to identify novel Toxoplasma gondii genes important for immune evasion.
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Walwyn, O., Skariah, S., Lynch, B., Kim, N., Ueda, Y., Vohora, N., Choe, J., Mordue, D. G. Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity. J. Vis. Exp. (97), e52556, doi:10.3791/52556 (2015).
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