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Un nuevo modelo de leve lesión cerebral traumática para ratas jóvenes
JoVE Journal
Medicina
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JoVE Journal Medicina
A Novel Model of Mild Traumatic Brain Injury for Juvenile Rats
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Un nuevo modelo de leve lesión cerebral traumática para ratas jóvenes

22,998 Views

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07:36 min

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December 08, 2014

DOI:

10.3791/51820-v

DOI:
10.3791/51820-v

•

07:36 min
December 08, 2014

•

16 Views
, , , , ,
1Alberta Children’s Hospital Research Institute,University of Calgary, 2Department of Psychiatry and Behavioral Neurosciences,Wayne State University School of Medicine & John D. Dingell VA Medical Center

Summary

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The modified weight-drop technique is an easy, cost-effective procedure used for the induction of mild traumatic brain injury in juvenile rats. This novel technique produces clinically relevant symptomology that will advance the study of mild traumatic brain injury (mTBI) and concussion.

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Mild Traumatic Brain InjuryMTBIJuvenile RatsWeight-drop TechniqueAccelerationDecelerationRotational ForcesPost-concussion SymptomologyRepetitive Brain InjuryBiomechanicsPathophysiology

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Cite this Article

Mychasiuk, R., Farran, A., Angoa-Perez, M., Briggs, D., Kuhn, D., Esser, M. J. A Novel Model of Mild Traumatic Brain Injury for Juvenile Rats. J. Vis. Exp. (94), e51820, doi:10.3791/51820 (2014).

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