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Stabilizing Hepatocellular Phenotype Using Optimized Synthetic Surfaces
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Chimica
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JoVE Journal Chimica
Stabilizing Hepatocellular Phenotype Using Optimized Synthetic Surfaces

Stabilizing Hepatocellular Phenotype Using Optimized Synthetic Surfaces

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08:50 min

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September 26, 2014

DOI:

10.3791/51723-v

DOI:
10.3791/51723-v

•

08:50 min
September 26, 2014

•

1 Views
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1MRC Centre for Regenerative Medicine,University of Edinburgh, 2School of Chemistry,University of Edinburgh, 3MRC Centre for Inflammation Research,University of Edinburgh

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This article will focus on developing polymer coated surfaces for long-term, stable culture of stem cell derived human hepatocytes.

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HepatocytePrimary HepatocyteStem Cell-derived HepatocyteCell PhenotypeBiological MatrixSynthetic Polymer CoatingPolyurethaneCell CultureLong-term CulturePhenotype StabilityHigh-throughput ScreeningCellular Therapy

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Cite this Article

Lucendo-Villarin, B., Cameron, K., Szkolnicka, D., Travers, P., Khan, F., Walton, J. G., Iredale, J., Bradley, M., Hay, D. C. Stabilizing Hepatocellular Phenotype Using Optimized Synthetic Surfaces. J. Vis. Exp. (91), e51723, doi:10.3791/51723 (2014).

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