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在乳腺癌细胞雌激素调节小分子RNA的剖析
JoVE Journal
Medicina
This content is Free Access.
JoVE Journal Medicina
Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells
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在乳腺癌细胞雌激素调节小分子RNA的剖析

19,737 Views

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16:24 min

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February 21, 2014

DOI:

10.3791/51285-v

DOI:
10.3791/51285-v

•

16:24 min
February 21, 2014

•

3 Views
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1Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry,University of Houston

Summary

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分子通过雌激素和小分子RNA的信号是在乳腺癌的发展和增长的关键。雌激素激活的雌激素受体，它是转录因子。许多转录因子能调节微RNA的表达，而雌激素调节的微小RNA可以使用不同的大规模的技术来成型。

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EstrogenEstrogen ReceptorBreast CancerMiRNAMicroarrayQPCRGene ExpressionPost-transcriptional RegulationOncogeneTumor SuppressorBiomarker

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Cite this Article

Katchy, A., Williams, C. Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells. J. Vis. Exp. (84), e51285, doi:10.3791/51285 (2014).

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