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August 01, 2012
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巨噬细胞发挥核心作用的动态平衡，并在许多组织的病理。这里介绍的协议描述消耗巨噬细胞的方法<em>在体内</em>，来自偏光巨噬细胞，骨髓穿刺，继转移到小鼠巨噬细胞。这些技术允许极化的巨噬细胞在健康和疾病中发挥的作用的决心。
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DepletionReconstitutionMacrophagesMiceInnate Immune ResponseAcquired Immune ResponseMacrophage DysfunctionDisease ProcessesInflammatory Bowel DiseasesPolarized PhenotypesClassically Activated MacrophagesAlternatively Activated MacrophagesIFN-gammaLPSIL-4IL-13InflammationInflammatory ResponseWhole Animal ModelDepleting MacrophagesComplex EnvironmentPhenotypically Defined Polarized MacrophagesBone Marrow Aspirates
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Weisser, S. B., van Rooijen, N., Sly, L. M. Depletion and Reconstitution of Macrophages in Mice. J. Vis. Exp. (66), e4105, doi:10.3791/4105 (2012).
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