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协同刺激信号封锁的同种抗原刺激诱导人外周血单个核细胞同种异体抗原特异性无能
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March 14, 2011
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本文介绍了一个简单的方法诱导人外周血单个核细胞同种异体抗原特异性无能。该技术可应用于临床，产生非同种异体的供体细胞。这些细胞输注可以提高免疫功能重建和减少异基因造血干细胞移植后的毒性。
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Davies, J. K., Barbon, C. M., Voskertchian, A. R., Nadler, L. M., Guinan, E. C. Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade. J. Vis. Exp. (49), e2673, doi:10.3791/2673 (2011).
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