This content is Free Access.
等位基因特异性基因表达检测，测试的遗传协会的功能基础
22,520 Views
•
10:17 min
•
November 03, 2010
DOI:
Summary
Automatically generated
遗传协会经常保持在功能级别上的原因不明。这种方法的目的是，通过分析细胞转录单核苷酸多态性杂合子基因表达，以评估的表型相关的遗传标记的影响。该技术可以精确测量，用MALDI - TOF质谱定量等位基因特异性引物延伸产品。
Explore More Videos
Allele-specific Gene Expression AssayGenetic AssociationsMolecular Level UnderstandingGene Expression MechanismDNA VariantsPhenotypesRelative Abundance Of TranscriptsRisk VariantsHeterozygous CellsDNA MarkersAllele FrequencyHaplotypic RelationshipCell TypesNucleic Acid ExtractionFibroblastsPrimary Cells
Read Article
Cite this Article
Paracchini, S., Monaco, A. P., Knight, J. C. An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations. J. Vis. Exp. (45), e2279, doi:10.3791/2279 (2010).
Copy