Engineering Cell-permeable Protein

Bernhard M&#252;nst; Christoph Patsch; Frank Edenhofer

doi:10.3791/1627

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Biologia

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Technische Cel-permeabel Protein

JoVE Journal
Biologia
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JoVE Journal Biologia

Engineering Cell-permeable Protein

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Technische Cel-permeabel Protein

14,252 Views

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21:08 min

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December 28, 2009

DOI:

10.3791/1627-v

DOI:

10.3791/1627-v

•

21:08 min

December 28, 2009

•

2 Views

Bernhard Münst¹, Christoph Patsch¹, Frank Edenhofer¹

¹Stem Cell Engineering Group, Institute of Reconstructive Neurobiology,University of Bonn – Life & Brain Center and Hertie Foundation

Summary

Eiwit transductie maakt de directe levering van biologisch actieve eiwitten in cellen. In tegenstelling tot conventionele methoden, zoals DNA-transfectie of virale transductie deze niet-invasieve paradigma maakt zeer efficiënte cellulaire manipulatie in een titreerbare manier te omzeilen cellulaire toxiciteit en het risico van oncogene transformatie door permanente genetische modificatie.

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Technische Cel-permeabel Protein

Summary

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