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Derivation of Enteric Neurons from Human Pluripotent Stem Cells

Derivation of Enteric Neurons from Human Pluripotent Stem Cells

May 17, 2024

Author Spotlight: Robust Culture of Human Enteric Neurons from Human Pluripotent Stem Cells

01:00 min
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Formation of Neural Crests from Human Pluripotent Stem Cells for Enteric Nervous System Research

00:50 min
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47 Views

Differentiation of Enteric Neural Crest Spheroid and Neuronal Induction from Human Pluripotent Stem Cells for Enteric Nervous System Research

03:24 min
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54 Views
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1Department of Cellular and Molecular Pharmacology,University of California, San Francisco, 2Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research,University of California, San Francisco, 3Program in Craniofacial Biology,University of California, San Francisco

Summary

Deriving enteric nervous system (ENS) lineages from human pluripotent stem cells (hPSC) provides a scalable source of cells to study ENS development and disease, and to use in regenerative medicine. Here, a detailed in vitro protocol to derive enteric neurons from hPSCs using chemically defined culture conditions is presented.

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