Rivista
Biologia dello sviluppo
Avian Embryonic Left Atrial Ligation Model for HLHS and Cardiovascular Research

Avian Embryonic Left Atrial Ligation Model for HLHS and Cardiovascular Research

June 16, 2023

Author Spotlight: Effect of Left Atrial Ligation on Avian Embryonic Hearts and HLHS Implications

01:59 min
•
749 Views

Left Atrial Ligation in Chick Embryos

02:58 min
•
200 Views
, , ,
1Department of Biomedical Sciences and Engineering,Koc University, 2Department of Mechanical Engineering,Koc University

Summary

Here, we present a detailed visual protocol for executing the left atrial ligation (LAL) model in the avian embryo. The LAL model alters the intracardiac flow, which changes wall shear stress loading, mimicking hypoplastic left heart syndrome. An approach to overcome the challenges of this difficult microsurgery model is presented.

Article