/

Immunologie et infection

/

Renal Subcapsular Transplantation of 2′-Deoxyguanosine-Treated Murine Embryonic Thymus in Nude Mice

Journal JoVE
Immunologie et infection

Un abonnement à JoVE est nécessaire pour voir ce contenu. Connectez-vous ou commencez votre essai gratuit.

Journal JoVE Immunologie et infection

Renal Subcapsular Transplantation of 2′-Deoxyguanosine-Treated Murine Embryonic Thymus in Nude Mice

Renal Subcapsular Transplantation of 2′-Deoxyguanosine-Treated Murine Embryonic Thymus in Nude Mice

10,317 Views

•

07:39 min

•

July 19, 2019

DOI:

10.3791/59657-v

DOI:

10.3791/59657-v

•

07:39 min

July 19, 2019

•

2 Views

Jianxue Wang^1,3,4, Guolin Chen^1,3,4, Qianwen Cui^2,3,4, Erfei Song^1,3,4, Weihua Tao¹, Wanqun Chen², Cunchuan Wang^1,3,4, Shiqi Jia^1,3,4

¹The First Affiliated Hospital,Jinan University, ²Department of Biochemistry and Molecular Biology, School of Basic Medical Science,Jinan University, ³The Institute of Clinical Medicine,Jinan University, ⁴Joint institute of Metabolic Medicine Between Jinan University and University of Hong Kong

Summary

We provide a simple and efficient method to transplant 2’-deoxyguanosine treated E18.5 thymus into the renal capsule of a nude mouse. This method should aide in the study of both thymic epithelial cells function and T cells maturation.

Explore More Videos

Renal Subcapsular Transplantation Murine Embryonic Thymus Nude Mice Thymus Transplantation Thymus Epithelial Cell Function T-cell Maturation 18.5 Thymus Transplantation 2′-deoxyguanosine Treatment Thymic Transplantation

Read Article