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Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941
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April 28, 2019
DOI:
1Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine,Medical University of Vienna, 2Department for Pharmaceutical Technology and Biopharmaceutics, Faculty of Life Sciences,University of Vienna, 3Ludwig Boltzmann Institute Applied Diagnostics, 4CBmed GmbH – Center for Biomarker Research in Medicine
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Here, we represent a protocol for the fully automated radiolabelling of [11C]SNAP-7941 and the analysis of the real-time kinetics of this PET-tracer on P-gp expressing and non-expressing cells.
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Vraka, C., Pichler, V., Pfaff, S., Balber, T., Hacker, M., Mitterhauser, M., Wadsak, W., Philippe, C. Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941. J. Vis. Exp. (146), e59557, doi:10.3791/59557 (2019).
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