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Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis (NASH) Resolution
Chapitres
- 00:04Titre
- 00:46Liver Biopsy
- 02:24Results: Representative Effects of the Non-alcoholic Steatohepatitis (NASH) Diet on Mouse Liver Inflammation and Steatosis
- 03:48Conclusion
In clinical settings, a liver biopsy is used to assess stages of non-alcoholic steatohepatitis (steatosis, inflammation, hepatocyte ballooning, and fibrosis). Here, we illustrate a survivable liver biopsy in mice which can be used for histological analyses to enable assessment of therapeutic agents in a manner more aligned with clinical trials.
