Journal
/
Sciences du comportement
/
The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
Journal JoVE
Sciences du comportement
Un abonnement à JoVE est nécessaire pour voir ce contenu.  Connectez-vous ou commencez votre essai gratuit.
Journal JoVE Sciences du comportement
The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice

DOI:
10.3791/58184-v

•

07:13 min

•

October 24, 2018

•

,
1School of Behavioral Science,The Academic College Tel-Aviv-Yaffo, 2Department of Education and Psychology,Open University

Chapitres

  • 00:00Titre
  • 00:44Unpredictable Chronic Mild Stress (UCMS) Protocol
  • 04:03Treatment Phase and Sucrose Preference Test
  • 05:22Results: UCMS Protocol Effectively Induces Anhedonia
  • 06:48Conclusion

Summary

Traduction automatique

Traduction automatique

Here we present the unpredictable chronic mild stress protocol in mice. This protocol induces a long-term depressive-like phenotype and enables to assess the efficacy of putative antidepressants in reversing the behavioral and neuromolecular depressive-like deficits.

Tags

Keywords: UCMS ProtocolChronic Mild StressAnhedoniaDepressionAnxietyPharmacological TreatmentsMouse Model

Article

Embed

AJOUTER À LA PLAYLIST

Usage Statistics

Vidéos Connexes

check_url/fr/58184?article_type=v

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
check_url/fr/58184?article_type=v

Mindfulness in Motion (MIM): An Onsite Mindfulness Based Intervention (MBI) for Chronically High Stress Work Environments to Increase Resiliency and Work Engagement
check_url/fr/58184?article_type=v

A Protocol for Housing Mice in an Enriched Environment
check_url/fr/58184?article_type=v

A Mouse Model of Subchronic and Mild Social Defeat Stress for Understanding Stress-induced Behavioral and Physiological Deficits
check_url/fr/58184?article_type=v

The Social Dimension of Stress: Experimental Manipulations of Social Support and Social Identity in the Trier Social Stress Test
check_url/fr/58184?article_type=v

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
check_url/fr/58184?article_type=v

A Protocol of Manual Tests to Measure Sensation and Pain in Humans
check_url/fr/58184?article_type=v

A New Method for Inducing a Depression-Like Behavior in Rats
check_url/fr/58184?article_type=v

Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget
check_url/fr/58184?article_type=v

Low-cost Protocol of Footprint Analysis and Hanging Box Test for Mice Applied the Chronic Restraint Stress

Read Article