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Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze
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Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze
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July 17, 2017
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Here we present a protocol for a mouse-specific test of cognition that does not require swimming. This test can be used to successfully distinguish controlled cortical impact-induced traumatic brain injury mice from sham controls.
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Cline, M. M., Ostlie, M. A., Cross, C. G., Garwin, G. G., Minoshima, S., Cross, D. J. Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze. J. Vis. Exp. (125), e55986, doi:10.3791/55986 (2017).
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