Journal
/
Immunologie et infection
/
Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity
Journal JoVE
Immunologie et infection
Un abonnement à JoVE est nécessaire pour voir ce contenu.  Connectez-vous ou commencez votre essai gratuit.
Journal JoVE Immunologie et infection
Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity

Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity

8,492 Views

•

10:10 min

•

November 08, 2016

DOI:

10.3791/54720-v

DOI:
10.3791/54720-v

•

10:10 min
November 08, 2016

•

4 Views
, , ,
1Department of Microbiology and Immunology,The Pennsylvania State University College of Medicine

Summary

Automatically generated

We present here a method to develop functional antigen (Ag)-specific regulatory T cells (Tregs) from induced pluripotent stem cells (iPSCs) for immunotherapy of autoimmune arthritis in a murine model.

Explore More Videos

Stem CellRegulatory T CellsAutoimmune ArthritisImmunotherapyAntigen-specificInduced Pluripotent Stem Cells (iPSCs)OP9 Feeder CellsFlt3-LigandIL-7

Read Article

Cite this Article

Haque, M., Fino, K., Sandhu, P., Song, J. Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity. J. Vis. Exp. (117), e54720, doi:10.3791/54720 (2016).

Download .ris file

Copy

Share Video

.

Copy