Cognitive deficits are common in about one third of patients with amyotrophic lateral sclerosis, a neurological condition leading to progressive impairments in speech and movement abilities. To conduct cognitive tests in patients unable to speak or write a reliable and easy to administer eye-tracking paradigm was developed.
Keller, J., Gorges, M., Aho-Özhan, H. E. A., Uttner, I., Schneider, E., Kassubek, J., Pinkhardt, E. H., Ludolph, A. C., Lulé, D. Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis. J. Vis. Exp. (116), e54634, doi:10.3791/54634 (2016).