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L'injection de cellules syngéniques murin de mélanome pour déterminer leur potentiel métastatique dans les Poumons
Journal JoVE
Médecine
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Journal JoVE Médecine
Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs
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L'injection de cellules syngéniques murin de mélanome pour déterminer leur potentiel métastatique dans les Poumons

17,237 Views

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07:31 min

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May 24, 2016

DOI:

10.3791/54039-v

DOI:
10.3791/54039-v

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07:31 min
May 24, 2016

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4 Views
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1Brain Tumor Center & Neuro-Oncology Unit, Department of Neurology,Beth Israel Deaconess Medical Center & Harvard Medical School, 2Division of Cancer Genetics, Department of Medicine,Beth Israel Deaconess Medical Center & Harvard Medical School

Summary

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Metastasis plays a profound role in the virulence of cancer, accounting for an estimated 90% of deaths. We report a protocol for a metastatic melanoma model in mice that is useful for determining the efficacy of therapeutic agents against this clinical phenomenon.

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Cite this Article

Timmons, J. J., Cohessy, S., Wong, E. T. Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs. J. Vis. Exp. (111), e54039, doi:10.3791/54039 (2016).

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