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幹細胞由来の中枢神経系ニューロンのネットワーク化培養における生物学的神経毒の機能評価
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons
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幹細胞由来の中枢神経系ニューロンのネットワーク化培養における生物学的神経毒の機能評価

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15:05 min

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February 05, 2015

DOI:

10.3791/52361-v

DOI:
10.3791/52361-v

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15:05 min
February 05, 2015

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3 Views
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1Research Division, Cellular Molecular Biology Branch,United States Army Medical Research Institute of Chemical Defense

Tags

Stem Cell-derived NeuronsCentral Nervous SystemNeurotoxinsClostridial NeurotoxinsBotulinum NeurotoxinTetanus NeurotoxinSynaptic ActivityElectrophysiologyMiniature Excitatory Post-synaptic CurrentsDose-dependent EffectsIn Vitro Model

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Hubbard, K., Beske, P., Lyman, M., McNutt, P. Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons. J. Vis. Exp. (96), e52361, doi:10.3791/52361 (2015).

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