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The Attentional Set Shifting Task: A Measure of Cognitive Flexibility in Mice
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Sciences du comportement
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Journal JoVE Sciences du comportement
The Attentional Set Shifting Task: A Measure of Cognitive Flexibility in Mice

The Attentional Set Shifting Task: A Measure of Cognitive Flexibility in Mice

26,678 Views

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09:15 min

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February 04, 2015

DOI:

10.3791/51944-v

DOI:
10.3791/51944-v

•

09:15 min
February 04, 2015

•

20 Views
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1Department of Pharmacology,University of Texas Health Science Center at San Antonio, 2Audie L. Murphy VA Hospital,South Texas Veteran’s Health Care System

Summary

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The goal of this protocol is to perform a behavioral assay such as the attentional set shifting task (AST) to assess prefrontal cortex-mediated cognitive flexibility in mice.

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Cognitive FlexibilityAttentional Set Shifting TaskPrefrontal CortexCognitive ImpairmentNeuropsychiatric DisordersNeurodevelopmental DisordersDepressionPTSDSchizophreniaAutismCognitive FunctionPreclinical Behavioral AssaysMouse ModelsFace ValidityConstruct ValidityPredictive Validity

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Cite this Article

Heisler, J. M., Morales, J., Donegan, J. J., Jett, J. D., Redus, L., O'Connor, J. C. The Attentional Set Shifting Task: A Measure of Cognitive Flexibility in Mice. J. Vis. Exp. (96), e51944, doi:10.3791/51944 (2015).

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